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In the English language we know the name of Yeshua as Jesus. In the modern Hebrew language we write His real name like this: ישוע.
Because we have to read from right to left in Hebrew, His name begins with the smallest letter of the Hebrew alphabet, the 'yod'. Yes, that little comma.
The Yod is the Y-sound in Hebrew. Jesus, or Yeshua, used that little letter to explain something about the Law: Do not think that I came to destroy the Law or the Prophets. I did not come to destroy but to fulfill. For assuredly, I say to you, till heaven and earth pass away, one jot or one tittle will by no means pass from the law till all is fulfilled (Matthew 5: 17-18).
Even the smallest things are important in the eyes of Jesus and can never be pushed aside by us. [see also my blog series: Law & Grace, an uneven match?]
Depending on the country in which you live and the language you speak, Jesus can be known as Jesus, Isa, Jezus, Izus, Jesi, Iesu and many more variations. The spelling of the name of Yeshua is not so important to me, because the meaning is the same in every language: The Lord is salvation.
What is important however, is this question: Do you know him? That is the most important question we ever have to answer for ourselves. And of course we can then extend that question to someone else.
I count everything as loss compared to the priceless privilege and supreme advantage of knowing Christ Jesus my Lord (Philippians 3: 8).